The SARNP Polyclonal Antibody (CAB13701) is a valuable tool for researchers studying SARNP, a protein involved in RNA processing and metabolism. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in applications such as Western blotting. By binding to SARNP, this antibody enables the detection and analysis of this important protein in a variety of cell types, making it ideal for investigations in molecular biology and RNA biology.SARNP, also known as SNRPC-associated RNA splicing factor, plays a crucial role in the splicing of pre-mRNA molecules, ensuring the accurate processing of genetic information.
Dysregulation of SARNP has been linked to various diseases, including cancer and neurological disorders, highlighting its potential as a therapeutic target. By studying the function of SARNP, researchers can gain insights into molecular mechanisms underlying these conditions and develop targeted therapies for effective treatment.
Product Name:
SARNP Rabbit Polyclonal Antibody
SKU:
CAB13701
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SARNP (NP_149073.1).
This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
84324
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SARNP Rabbit pAb (CAB13701) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
