SAR-CoV-2 CoV-2-S1 (319-541) Recombinant Protein (RPPB5331)
- SKU:
- RPPB5331
- Product Type:
- Recombinant Protein
- Species:
- Viral
- Uniprot:
- QHD43416.1
Description
Product Name: | SAR-CoV-2 CoV-2-S1 (319-541) Recombinant Protein |
Product Code: | RPPB5331 |
Size: | 5µg |
Species: | SAR-CoV-2 |
Target: | CoV-2-S1 (319-541) |
Source: | HEK293 Cells |
Physical Appearance: | Lyophilized freezed dried powder. |
Formulation: | CoV-2 S1�RBD�protein�is lyophilized from 1x PBS pH-7.4 + 10% trehalose. |
Solubility: | It is recommended to reconstitute the lyophilized CoV-2 S1 protein in sterile 18M-cm H2O at a�concentration�of 0.2mg/ml and not less than 0.1mg/ml, which can then be further diluted to other aqueous solutions. |
Stability: | Lyophilized Cov-2 S1 Glycoprotein RBD although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CoV2 Spike protein should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
Purity: | Protein is >90% pure as determined SDS-PAGE. |
UniProt Code: | QHD43416.1 |
A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019.The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) �in humans.While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.
The HEK293 derived Biotinylated recombinant protein contains the Coronavirus 2019 Spike Glycoprotein S1 Receptor Binding Domain [ RBD ], Wuhan-Hu-1 strain, amino acids 319-541 fused to His tag & AVI tag at C-terminal�and having a molecular mass of �28.7kDa.