SAP18 Rabbit Polyclonal Antibody (CAB4397)
- SKU:
- CAB4397
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SAP18
- 2HOR0202
- SAP18P
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SAP18 Rabbit Polyclonal Antibody |
SKU: | CAB4397 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-172 of human SAP18 (NP_005861.2). |
Sequence: | AVES RVTQ EEIK KEPE KPID REKT CPLL LRVF TTNN GRHH RMDE FSRG NVPS SELQ IYTW MDAT LKEL TSLV KEVY PEAR KKGT HFNF AIVF TDVK RPGY RVKE IGST MSGR KGTD DSMT LQSQ KFQI GDYL DIAI TPPN RAPP PSGR MRPY |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | SAP18P; 2HOR0202; SAP18 |
Positive Sample: | SW480 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, Nucleus speckle. |
Calculated MW: | 18kDa |
Observed MW: | 18kDa |
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.
Purification Method: | Affinity purification |
Gene ID: | 10284 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |