UniProt Protein Function: | SAMSN1: an adaptor and scaffold protein containing an SH3 and a SAM (sterile alpha motif) domain. Its expression is induced by B cell activation signals. Two alternatively spliced isoforms have been described.Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: 21q11Cellular Component: ruffle; cytosol; nucleusMolecular Function: phosphotyrosine bindingBiological Process: negative regulation of peptidyl-tyrosine phosphorylation; negative regulation of adaptive immune response; negative regulation of B cell activation |
UniProt Protein Details: | |
NCBI Summary: | SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9NSI8 |
NCBI GenInfo Identifier: | 48762709 |
NCBI Gene ID: | 64092 |
NCBI Accession: | NP_071419.3 |
UniProt Secondary Accession: | Q9NSI8,Q8NFF7, Q9C041, B3KWJ3, F8WAA1 |
UniProt Related Accession: | Q9NSI8 |
Molecular Weight: | 49,627 Da |
NCBI Full Name: | SAM domain-containing protein SAMSN-1 isoform 1 |
NCBI Synonym Full Names: | SAM domain, SH3 domain and nuclear localization signals 1 |
NCBI Official Symbol: | SAMSN1Â Â |
NCBI Official Synonym Symbols: | SLy2; HACS1; NASH1; SASH2; SH3D6BÂ Â |
NCBI Protein Information: | SAM domain-containing protein SAMSN-1 |
UniProt Protein Name: | SAM domain-containing protein SAMSN-1 |
UniProt Synonym Protein Names: | Hematopoietic adaptor containing SH3 and SAM domains 1; Nash1; SAM domain, SH3 domain and nuclear localization signals protein 1; SH3-SAM adaptor protein |
Protein Family: | SAM domain-containing protein |
UniProt Gene Name: | SAMSN1Â Â |
UniProt Entry Name: | SAMN1_HUMAN |