The SAMD7 Polyclonal Antibody (PACO17047) is a valuable tool for research involving SAMD7, a protein involved in cell signaling and regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in various experimental applications, including Western blot analysis.SAMD7 is known to play a role in cellular processes such as cell growth, differentiation, and apoptosis. By targeting the SAMD7 protein, this antibody enables the detection and analysis of SAMD7 expression in different cell types, making it suitable for studies in developmental biology, cancer research, and other related fields.
The importance of SAMD7 in regulating cell behaviors and functions makes it a promising target for further investigation in diseases such as cancer, neurodevelopmental disorders, and genetic syndromes. Understanding the mechanisms by which SAMD7 operates can provide insights into potential therapeutic strategies for these conditions. Researchers can utilize this antibody to advance their understanding of SAMD7 and its implications in various biological processes.
Antibody Name:
SAMD7 Antibody (PACO17047)
Antibody SKU:
PACO17047
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Fusion protein of human SAMD7
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO17047(SAMD7 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17047(SAMD7 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Background:
SAMD7 (Sterile α motif domain-containing protein 7), is a 446 amino acid, protein encoded by the SAMD7 gene which maps to human chromosome 3. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.
Synonyms:
sterile α motif domain containing 7
UniProt Protein Function:
Involved in the regulation of gene expression in the retina. It functions as a negative regulator of CRX-controlled genes.
