The SAMD7 Polyclonal Antibody (PACO17046) is a valuable tool for research involving the SAMD7 protein, a member of the SAM domain family with roles in development and disease. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot analysis. By targeting the SAMD7 protein, researchers can identify and study this molecule in various cell types, allowing for investigation in developmental biology and disease mechanisms.SAMD7 is known for its involvement in various cellular processes, including cell growth, differentiation, and signaling pathways.
Its functions have been linked to development disorders and cancers, making it a compelling target for research in genetics and oncology. Investigating the role of SAMD7 can provide insights into its contribution to disease pathogenesis and potential therapeutic strategies for related conditions.Overall, the SAMD7 Polyclonal Antibody offers researchers a reliable tool for studying the SAMD7 protein and its implications in cellular processes and diseases, paving the way for advancements in biomedical research and the development of targeted therapies.
Antibody Name:
SAMD7 Antibody (PACO17046)
Antibody SKU:
PACO17046
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Fusion protein of human SAMD7
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17046(SAMD7 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17046(SAMD7 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200).
Background:
SAMD7 (Sterile α motif domain-containing protein 7), is a 446 amino acid, protein encoded by the SAMD7 gene which maps to human chromosome 3. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.
Synonyms:
sterile α motif domain containing 7
UniProt Protein Function:
Involved in the regulation of gene expression in the retina. It functions as a negative regulator of CRX-controlled genes.
