The SAMD4B Polyclonal Antibody (PAC020387) is a valuable tool for researchers studying SAMD4B, a protein involved in RNA metabolism and regulation of gene expression. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By binding to the SAMD4B protein, this antibody allows for the detection and analysis of SAMD4B in various cell types, making it ideal for studies in molecular biology and RNA processing.SAMD4B is known to play a crucial role in the degradation of mRNA and regulation of RNA stability, making it a key player in gene expression control. Dysregulation of SAMD4B has been implicated in various diseases, including cancer and neurological disorders, highlighting its importance in cellular function.
By investigating the function and expression of SAMD4B, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets.Overall, the SAMD4B Polyclonal Antibody (PAC020387) is a valuable tool for researchers interested in studying RNA metabolism, gene expression, and the role of SAMD4B in disease pathogenesis. Its high specificity and reliability make it a trusted reagent for experiments aimed at unraveling the complexities of SAMD4B function in cellular processes.
Antibody Name:
SAMD4B Antibody (PACO20387)
Antibody SKU:
PACO20387
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human SAMD4B
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20387(SAMD4B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
SMGB; hSmaug2
Synonyms:
sterile α motif domain containing 4B
UniProt Protein Function:
SAMD4B: Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A. Belongs to the SMAUG family.
UniProt Protein Details:
Protein type:Unknown function
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: cytoplasm; nucleus
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
