Description
SAMD4B Antibody (PACO12020)
The SAMD4B Polyclonal Antibody (PAC012020) is a valuable tool for researchers studying SAMD4B, a gene involved in RNA processing and regulation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SAMD4B protein, this antibody allows for precise detection and analysis in a variety of cell types, making it a versatile tool for studies in molecular biology and gene regulation.SAMD4B is known to play a crucial role in mRNA decay and regulation, impacting gene expression and protein production.
Research into SAMD4B is essential for understanding how RNA processing is controlled and how dysregulation of this gene can lead to diseases such as cancer, neurodegenerative disorders, and developmental abnormalities. By studying SAMD4B and its functions, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets.
Antibody Name: | SAMD4B Antibody (PACO12020) |
Antibody SKU: | PACO12020 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human SAMD4B |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | sterile α motif domain containing 4B;SAMD4B;FLJ10211;MGC99832;SMGB ; |
UniProt Protein Function: | SAMD4B: Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A. Belongs to the SMAUG family. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: cytoplasm; nucleus Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent |
UniProt Code: | Q5PRF9 |
NCBI GenInfo Identifier: | 74736136 |
NCBI Gene ID: | 55095 |
NCBI Accession: | Q5PRF9.1 |
UniProt Secondary Accession: | Q5PRF9,Q6P194, A5Z0M6, |
UniProt Related Accession: | Q5PRF9 |
Molecular Weight: | Calculated MW: 75kDaObserved MW: 80kDa |
NCBI Full Name: | Protein Smaug homolog 2 |
NCBI Synonym Full Names: | sterile alpha motif domain containing 4B |
NCBI Official Symbol: | SAMD4BÂ Â |
NCBI Official Synonym Symbols: | SMGB; Smaug2Â Â |
NCBI Protein Information: | protein Smaug homolog 2; hSmaug2; smaug 2; smaug homolog B; SAM domain-containing protein 4B; sterile alpha motif domain-containing protein 4B |
UniProt Protein Name: | Protein Smaug homolog 2 |
UniProt Synonym Protein Names: | Sterile alpha motif domain-containing protein 4B; SAM domain-containing protein 4B |
Protein Family: | Protein |
UniProt Gene Name: | SAMD4BÂ Â |
UniProt Entry Name: | SMAG2_HUMAN |