Anti-SAMD4A Antibody (PACO20384)

SAMD4A Antibody (PACO20384)

SKU:

PACO20384

Product Type:

Antibody

Reactivity:

Human

Host Species:

Rabbit

Isotype:

IgG

Applications:

ELISA

IHC

Antibody Type:

Polyclonal Antibody

Conjugation:

Unconjugated

Description

Description

DatasheetMSDS

SAMD4A Antibody (PACO20384)

The SAMD4A Polyclonal Antibody (PACO20384) is a valuable tool for researchers studying SAMD4A, a protein involved in mRNA decay and cellular metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and is optimized for Western blot applications. By targeting the SAMD4A protein, researchers can investigate its role in various cellular processes, including RNA turnover and gene expression regulation.SAMD4A is known to play a critical role in post-transcriptional gene regulation, making it a key player in maintaining cellular homeostasis.

Dysregulation of SAMD4A has been implicated in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes, highlighting its potential as a therapeutic target. By studying SAMD4A using this antibody, researchers can gain valuable insights into its function and its impact on cellular physiology, aiding in the development of novel treatments for related diseases.

SAMD4A Antibody (PACO12019)

€459

Product Code:

PACO12019

Isotype:

IgG

Antibody Type:

Polyclonal Antibody

SAMD4A Antibody (PACO20385)

€339

Product Code:

PACO20385

Isotype:

IgG

Antibody Type:

Polyclonal Antibody

Immunofluorescence staining of MCF-7 cells with PACO64925 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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RIMS4 Antibody (PACO64925)

€319

Product Code:

PACO64925

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Western Blot<br />
Positive WB detected in: Mouse heart tissue,Mouse kidney tissue<br />
All lanes: ompF antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 57 kDa<br />
Observed band size: 57 kDa<br /> — Choose Options

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Ang4 Antibody (PACO64593)

€339

Product Code:

PACO64593

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Immunofluorescence staining of NIH/3T3 cells with PACO64869 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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OR13C8 Antibody (PACO64869)

€319

Product Code:

PACO64869

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Immunofluorescence staining of Hela cells with PACO64949 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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SIM1 Antibody (PACO64949)

€339

Product Code:

PACO64949

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Western Blot<br />
Positive WB detected in: Escherichia coli lysate<br />
All lanes: OTSB antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 30 kDa<br />
Observed band size: 30 kDa<br /> — Choose Options

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otsB Antibody (PACO64885)

€339

Product Code:

PACO64885

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

IHC image of PACO64929 diluted at 1:300 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. — Choose Options

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RNF122 Antibody (PACO64929)

€319

Product Code:

PACO64929

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Immunofluorescence staining of SH-SY5Y cells with PACO64589-IF at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). — Choose Options

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AGO4 Antibody (PACO64589)

€319

Product Code:

PACO64589

Antibody Type:

Polyclonal Antibody

Isotype:

IgG

Antibody Name:	SAMD4A Antibody (PACO20384)
Antibody SKU:	PACO20384
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human SAMD4A

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:	Sterile α motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein.
Synonyms:	sterile α motif domain containing 4A

UniProt Protein Function:	Function: Acts as a translational repressor of SRE-containing messengers. Ref.6Subcellular location: Cytoplasm. Cell projection dendrite By similarity. Cell junction synapse synaptosome By similarity. Note: Enriched in synaptoneurosomes By similarity. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1. Ref.6Sequence similarities: Belongs to the SMAUG family.Contains 1 SAM (sterile alpha motif) domain.Sequence caution: The sequence AAH57838.1 differs from that shown. Reason: Intron retention.The sequence AAP97302.1 differs from that shown. Reason: Intron retention.
UniProt Protein Details:
NCBI Summary:	Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).[supplied by OMIM, Mar 2008]
UniProt Code:	Q9UPU9
NCBI GenInfo Identifier:	1708342410
NCBI Gene ID:	23034
NCBI Accession:	NM_015589.6
UniProt Secondary Accession:	Q9UPU9
UniProt Related Accession:	Q9UPU9
Molecular Weight:
NCBI Full Name:	Homo sapiens sterile alpha motif domain containing 4A (SAMD4A), transcript variant 1, mRNA
NCBI Synonym Full Names:	sterile alpha motif domain containing 4A
NCBI Official Symbol:	SAMD4A
NCBI Official Synonym Symbols:	SMG; SMGA; SAMD4; SMAUG; SMAUG1
NCBI Protein Information:	protein Smaug homolog 1
UniProt Protein Name:	Protein Smaug homolog 1
UniProt Synonym Protein Names:	Sterile alpha motif domain-containing protein 4A
Protein Family:	Protein
UniProt Gene Name:	SAMD4A
UniProt Entry Name:	SMAG1_HUMAN

SAMD4A Antibody (PACO20384)

Description

SAMD4A Antibody (PACO20384)

Overview

Properties

Product Images

Additional Information

Related Products

SAMD4A Antibody (PACO20384)

Description

SAMD4A Antibody (PACO20384)

Overview

Properties

Product Images

Additional Information

Related Products

Related Products

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