The SAM68 Rabbit Monoclonal Antibody (CAB3886) is a valuable tool for researchers studying SAM68, a multifunctional RNA-binding protein involved in various cellular processes. This antibody, developed using rabbit monoclonal technology, offers high specificity and sensitivity for detecting SAM68 in human samples. Validated for use in Western blot and immunohistochemistry applications, it allows for precise localization and quantification of SAM68 in different cell types.SAM68 plays a crucial role in regulating alternative splicing, mRNA stability, and translation, making it a key player in gene expression regulation.
Dysregulation of SAM68 has been implicated in various diseases, including cancer and neurological disorders, making it an attractive target for therapeutic intervention. Understanding the function and regulation of SAM68 is essential for unraveling its precise roles in these pathologies and developing targeted treatments for disease management.
Product Name:
KHDRBS1/Sam68 Rabbit Monoclonal Antibody
SKU:
CAB3886
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KHDRBS1 (Q07666).
This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10657
Clone Number:
ARC0858
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using KHDRBS1/KHDRBS1/Sam68 Rabbit mAb (CAB3886) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
