The SALL4 Polyclonal Antibody (CAB16193) is a vital tool for researchers studying the role of SALL4, a transcription factor essential for stem cell pluripotency and embryonic development. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it suitable for a variety of research applications, including Western blotting.SALL4 is known for its crucial function in self-renewal and maintenance of stem cells, making it a key player in regenerative medicine and cancer research.
Its aberrant expression has been linked to various tumors, underscoring the importance of understanding its role in both normal and pathological conditions. By targeting SALL4 with this antibody, researchers can investigate its mechanisms of action and potentially identify novel therapeutic targets for diseases such as cancer.
Product Name:
SALL4 Rabbit Polyclonal Antibody
SKU:
CAB16193
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 853-1053 of human Sall4 (NP_065169.1).
This gene encodes a zinc finger transcription factor thought to play a role in the development of abducens motor neurons. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
57167
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Sall4 Rabbit pAb (CAB16193) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
