The SALL2 Polyclonal Antibody (PAC012018) is a valuable tool for researchers studying the SALL2 protein, a transcription factor involved in developmental processes and gene regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SALL2 protein, researchers can accurately detect and analyze its expression in various cell types, making it a versatile tool for studies in developmental biology and cancer research.
SALL2, also known as Spalt-like transcription factor 2, plays a crucial role in controlling gene expression and modulating cellular processes during development. Dysregulation of SALL2 expression has been associated with various developmental disorders and cancer progression, making it an important target for further investigation. By understanding the function of SALL2, researchers can potentially uncover new insights into disease mechanisms and develop targeted therapies for related conditions.
Probable transcription factor that plays a role in eye development before, during, and after optic fissure closure.
NCBI Summary:
This gene encodes a protein containing multiple zinc finger domains. The encoded protein functions in optical fissure closure during development of the eye in the embryo. Mutations in this gene are associated with ocular coloboma. [provided by RefSeq, Jul 2016]
