The SAFB2 Polyclonal Antibody (CAB4330) is a valuable tool for researchers studying SAFB2, a multifunctional protein involved in various cellular processes including gene regulation and RNA processing. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to SAFB2, the antibody enables precise detection and analysis of this essential protein in a range of cell types.SAFB2, also known as a scaffold attachment factor B2, is known to play a crucial role in chromatin organization and transcriptional regulation.
Its involvement in gene expression and RNA splicing make it a key player in cellular function, with potential implications in cancer biology and developmental processes. Research on SAFB2 can provide insights into the mechanisms underlying various diseases and may lead to the development of targeted therapeutic approaches.Overall, the SAFB2 Polyclonal Antibody offers a reliable solution for investigating the functions and interactions of SAFB2, making it an essential tool for studies in molecular biology, cell biology, and cancer research.
Product Name:
SAFB2 Rabbit Polyclonal Antibody
SKU:
CAB4330
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human SAFB2 (NP_055464.1).
The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes.
Purification Method:
Affinity purification
Gene ID:
9667
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SAFB2 antibody (CAB4330) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
