SAA1 Rabbit Polyclonal Antibody (CAB1655)
- SKU:
- CAB1655
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | SAA1 Rabbit Polyclonal Antibody |
SKU: | CAB1655 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-122 of human SAA1 (NP_000322.2). |
Sequence: | RSFF SFLG EAFD GARD MWRA YSDM REAN YIGS DKYF HARG NYDA AKRG PGGA WAAE VISD AREN IQRF FGHG AEDS LADQ AANE WGRS GKDP NHFR PAGL PEKY |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SAA; PIG4; SAA2; TP53I4; SAA1 |
Positive Sample: | SW480 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 12kDa |
Observed MW: | 14kDa |
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
Purification Method: | Affinity purification |
Gene ID: | 6288 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |