The Anti-S1PR3 Polyclonal Antibody (CAB1404) is specifically designed for research involving the S1PR3 protein, a member of the sphingosine-1-phosphate receptor family that plays a crucial role in various cellular processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.S1PR3 is known to be involved in the regulation of immune responses, cell migration, and vascular physiology, making it a key target for studies in immunology, oncology, and cardiovascular research. By binding to the S1PR3 protein, this antibody enables researchers to detect and analyze its expression in different cell types, allowing for a deeper understanding of its role in various physiological and pathological conditions.
With its ability to target S1PR3, this antibody is instrumental in uncovering the mechanisms underlying diseases such as cancer, autoimmune disorders, and cardiovascular diseases, where S1PR3 has been implicated. By elucidating the function of S1PR3, researchers can pave the way for novel therapeutic interventions that target this protein for the treatment of these conditions.
Product Name:
S1PR3 Rabbit Monoclonal Antibody
SKU:
CAB1404
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human S1PR3 (Q99500).
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.
Purification Method:
Affinity purification
Gene ID:
1903
Clone Number:
ARC1877
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using S1PR3 Rabbit mAb (CAB1404) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.