The S100A8 Polyclonal Antibody (CAB15315) is a powerful tool for researchers studying S100A8, a calcium-binding protein involved in inflammation and immune response regulation. This antibody is raised in rabbits and is highly specific for human samples, making it ideal for use in Western blot experiments.S100A8, also known as calgranulin A, plays a critical role in various inflammatory processes and has been implicated in diseases such as cancer, inflammatory bowel disease, and rheumatoid arthritis. By binding to the S100A8 protein, this antibody enables researchers to detect and analyze its expression in different cell types, offering valuable insights into its function in both physiological and pathological conditions.
With its ability to target S100A8, the CAB15315 antibody is a valuable tool for immunology and cancer research, providing researchers with the opportunity to better understand the role of S100A8 in inflammation and immune regulation. Its use may lead to the development of new therapeutic strategies for diseases where S100A8 dysregulation is implicated.
Product Name:
S100A8 Rabbit Polyclonal Antibody
SKU:
CAB15315
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-93 of human S100A8 (NP_002955.2).
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6279
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using S100A8 Rabbit pAb (CAB15315) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
