S100A7/Psoriasin Polyclonal Antibody (CAB22026)
- SKU:
- CAB22026
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- IHC
Frequently bought together:
Description
| Product Name: | S100A7/Psoriasin Polyclonal Antibody |
| SKU: | CAB22026 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-101 of human S100A7/Psoriasin (NP_002954.2). |
| Sequence: | SNTQ AERS IIGM IDMF HKYT RRDD KIEK PSLL TMMK ENFP NFLS ACDK KGTN YLAD VFEK KDKN EDKK IDFS EFLS LLGD IATD YHKQ SHGA APCS GGSQ |
| Tested Applications: | WB IHC-P ELISA |
| Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 |
| Synonyms: | PSOR1; S100A7c; S100A7/Psoriasin |
| Positive Sample: | SK-BR-3 |
| Conjugate: | Unconjugated |
| Cellular Localization: | cytoplasm, cytosol, endoplasmic reticulum, extracellular region, extracellular space, focal adhesion, nucleus |
| Calculated MW: | 11kDa |
| Observed MW: | 12kDa |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.
| Purification Method: | Affinity purification |
| Gene ID: | 6278 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
 | Western blot analysis of lysates from SK-BR-3 cells, using S100A7/Psoriasin Rabbit pAb (CAB22026) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s. |
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