The S100A6 Polyclonal Antibody is a valuable tool for researchers studying S100A6, a calcium-binding protein involved in a variety of cellular processes. This antibody, produced in rabbits, shows high reactivity with human samples and is optimized for use in Western blot applications. By specifically binding to the S100A6 protein, this antibody allows for precise detection and analysis of S100A6 expression in different cell types.S100A6 is known for its role in regulating cell cycle progression, cell differentiation, and cell migration, making it a key player in cancer progression and metastasis.
Research into the function of S100A6 is crucial for understanding its potential implications in cancer development and identifying new therapeutic targets.By using the S100A6 Polyclonal Antibody, researchers can further explore the molecular mechanisms underlying S100A6's involvement in cancer and other cellular processes. This antibody is a valuable tool for studies in oncology, cell biology, and drug discovery, providing important insights into the role of S100A6 in health and disease.
Product Name:
S100A6 Polyclonal Antibody
SKU:
CAB21819
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human S100A6(NP_055439.1).
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Purification Method:
Affinity purification
Gene ID:
6277
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251 MG cells using S100A6 Rabbit pAb(CAB21819) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
