The S100A5 Polyclonal Antibody (CAB14779) is a powerful tool for researchers studying S100A5, a member of the S100 family of calcium-binding proteins. This polyclonal antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By binding specifically to the S100A5 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in the fields of immunology and cancer research.S100A5 is known to play a role in various cellular processes, including cell cycle regulation, differentiation, and cell growth.
Its involvement in tumor development and progression has sparked interest in exploring its potential as a therapeutic target in cancer treatment. Researchers studying S100A5 aim to unlock its functions and mechanisms, paving the way for the development of novel therapies and diagnostic tools for cancer and other diseases. The S100A5 Polyclonal Antibody is a valuable asset in these endeavors, offering reliable and specific detection of S100A5 to support groundbreaking research initiatives.
Product Name:
S100A5 Rabbit Polyclonal Antibody
SKU:
CAB14779
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100A5 (NP_002953.2).
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain.
Purification Method:
Affinity purification
Gene ID:
6276
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251MG cells, using S100A5 Rabbit pAb (CAB14779) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
