The S100A2 Polyclonal Antibody (CAB12647) is a valuable tool for researchers studying the S100A2 protein, a member of the S100 family of calcium-binding proteins known for their involvement in cell signaling and regulation. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications.S100A2 plays a role in various cellular processes, including cell growth, differentiation, and apoptosis. Its dysregulation has been implicated in multiple diseases, including cancer, making it a promising target for therapeutic interventions.
By detecting and analyzing S100A2 expression levels in different cell types, this antibody enables researchers to further explore the protein's function and potential as a biomarker in cancer research and beyond.With its specificity and sensitivity, the S100A2 Polyclonal Antibody is a valuable tool for investigating the biological functions and disease implications of the S100A2 protein, ultimately contributing to advancements in the fields of cancer biology and molecular medicine.
Product Name:
S100A2 Rabbit Polyclonal Antibody
SKU:
CAB12647
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human S100A2 (NP_005969.1).
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.
Purification Method:
Affinity purification
Gene ID:
6273
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using S100A2 Rabbit pAb (CAB12647) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
