The Protein S100-A14 Polyclonal Antibody (CAB10394) is a vital tool for researchers studying the S100-A14 protein, which belongs to the S100 family of calcium-binding proteins. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it an excellent choice for Western blot applications.S100-A14 is known to play a role in various cellular processes, including cell differentiation, proliferation, and migration. Its dysregulation has been linked to several diseases, including cancer, neurodegenerative disorders, and inflammatory conditions.
The S100-A14 Polyclonal Antibody enables accurate detection and analysis of this protein in different cell types, facilitating research in areas such as oncology, neuroscience, and immunology.By using this antibody, researchers can gain valuable insights into the mechanisms underlying S100-A14's functions and its implications in disease pathogenesis. Better understanding of this protein could lead to the development of novel therapeutic strategies targeting S100-A14 for the treatment of various diseases.
Product Name:
S100A14 Rabbit Polyclonal Antibody
SKU:
CAB10394
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human S100A14 (NP_065723.1).
This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).
Purification Method:
Affinity purification
Gene ID:
57402
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using S100A14 Rabbit pAb (CAB10394) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
