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S100A12 Rabbit Polyclonal Antibody (CAB12499)

SKU:
CAB12499
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 1 Anti-S100A12 Antibody CAB12499
  • Immunology Antibodies 1 Anti-S100A12 Antibody CAB12499
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:S100A12 Rabbit Polyclonal Antibody
SKU:CAB12499
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100A12 (NP_005612.1).
Sequence:MTKL EEHL EGIV NIFH QYSV RKGH FDTL SKGE LKQL LTKE LANT IKNI KDKA VIDE IFQG LDAN QDEQ VDFQ EFIS LVAI ALKA AHYH THKE
Tested Applications:IHC-P ELISA
Recommended Dilution:IHC-P,1:100 - 1:500
Synonyms:p6; CAGC; CGRP; MRP6; CAAF1; MRP-6; ENRAGE; S100A12
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Cytoplasm, Peripheral membrane protein, Secreted, cytoskeleton.
Calculated MW:10kDa

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

Purification Method:Affinity purification
Gene ID:6283
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageImmunohistochemistry analysis of paraffin-embedded human colon carcinoma using S100A12 Rabbit pAb (CAB12499) at dilution of 1:300 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

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