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S100A12/CGRP Monoclonal Antibody

SKU:
CAB23912
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €529
Frequently bought together:

Description

S100A12/CGRP Monoclonal Antibody (CAB23912)

The S100A12/ CGRP Monoclonal Antibody is a cutting-edge tool for researchers studying the roles of S100A12 and CGRP in various biological processes. This antibody, generated using advanced monoclonal antibody technology, exhibits high specificity and sensitivity for detecting S100A12 and CGRP proteins in samples, making it ideal for use in a variety of experimental applications such as immunohistochemistry, ELISA, and flow cytometry.S100A12 is a member of the S100 family of calcium-binding proteins and has been implicated in inflammation, immune regulation, and various disease processes. CGRP, on the other hand, is a neuropeptide involved in pain transmission, vasodilation, and neurogenic inflammation.

By using this monoclonal antibody, researchers can gain valuable insights into the functions and interactions of these proteins in physiological and pathological conditions.Whether studying inflammation, neurobiology, or autoimmune disorders, the S100A12/ CGRP Monoclonal Antibody offers a reliable and reproducible tool for investigating the roles of these important proteins. Its specificity and high affinity ensure accurate and trustworthy results, making it a valuable asset for any laboratory conducting research in these fields.

Product Name:S100A12/CGRP Monoclonal Antibody
Product Code:CAB23912
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC61785
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:293F transfected by S100A12/CGRP
Cellular Location:Cell membrane, Cytoplasm, Peripheral membrane protein, Secreted, cytoskeleton

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100A12/CGRP (NP_005612.1).
Sequence:MTKLE EHLEG IVNIF HQYSV RKGHF DTLSK GELKQ LLTKE LANTI KNIKD KAVID EIFQG LDANQ DEQVD FQEFI SLVAI ALKAA HYHTH KE
Synonyms:p6, CAGC, CGRP, MRP6, CAAF1, MRP-6, ENRAGE
Calculated MW:10kDa
Observed MW:11kDa

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