The S100A11 Polyclonal Antibody is a valuable tool for researchers studying S100A11, a member of the S100 protein family implicated in various cellular processes, including inflammation, apoptosis, and cancer progression. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the S100A11 protein, this antibody allows for the detection and analysis of S100A11 in a variety of cell types, making it ideal for studies in cancer biology and inflammatory diseases.
S100A11 plays a crucial role in tumor growth, metastasis, and chemoresistance, making it a promising target for cancer therapy research. Additionally, its involvement in inflammation and apoptosis suggests potential implications in autoimmune disorders and other inflammatory conditions. Understanding the function of S100A11 is essential for developing targeted therapies that combat cancer progression and regulation of inflammatory responses.
Product Name:
S100A11 Polyclonal Antibody
SKU:
CAB21929
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human S100A11 (NP_005611.1).
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
Purification Method:
Affinity purification
Gene ID:
6282
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using S100A11 Rabbit pAb (CAB21929) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
