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S100/S100A1 Rabbit Monoclonal Antibody (CAB19107)

SKU:
CAB19107
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:S100/S100A1 Rabbit Monoclonal Antibody
SKU:CAB19107
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 2-94 of human S100/S100A1 (P23297).
Sequence:GSEL ETAM ETLI NVFH AHSG KEGD KYKL SKKE LKEL LQTE LSGF LDAQ KDVD AVDK VMKE LDEN GDGE VDFQ EYVV LVAA LTVA CNNF FWEN S
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:S100; S100A; S100-alpha; S100/S100A1
Positive Sample:Mouse lung,Mouse kidney,Mouse heart
Conjugate:Unconjugated
Cellular Localization:Cytoplasm.
Calculated MW:11kDa
Observed MW:11kDa

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

Purification Method:Affinity purification
Gene ID:6271
Clone Number:ARC0404
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using S100/S100A1 antibody (CAB19107) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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