The S100 Beta Rabbit Monoclonal Antibody (CAB19108) is a cutting-edge tool for researchers studying the S100 Beta protein, which is involved in various cellular processes, including regulation of protein phosphorylation, transcription factors, microtubule assembly, and interaction with cytoskeletal components. This antibody, derived from rabbit monoclonal sources, exhibits high specificity and sensitivity towards human S100 Beta samples, making it an excellent choice for Western blot and immunohistochemistry applications.S100 Beta is a member of the S100 family of proteins that are implicated in numerous diseases, including neurological disorders, cancer, and inflammatory conditions.
By targeting S100 Beta, researchers can gain valuable insights into the pathogenesis and progression of these diseases, ultimately leading to the development of new diagnostic tools and therapeutic strategies.This S100 Beta Rabbit Monoclonal Antibody is a versatile tool for investigating the role of S100 Beta in various biological processes and disease states. Its high specificity and sensitivity make it an essential reagent for researchers working in the fields of neuroscience, oncology, and immunology. Unlock the potential of S100 Beta research with this cutting-edge antibody.
Product Name:
S100B Rabbit Monoclonal Antibody
SKU:
CAB19108
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100B (NP_006263.1).
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Purification Method:
Affinity purification
Gene ID:
6285
Clone Number:
ARC50351
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat brain, using S100B Rabbit mAb (CAB19108) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
