The S antibody (PACO34410) offered by Assay Genie is a highly specific and sensitive tool for research involving the S protein. This polyclonal antibody, derived from rabbits, boasts exceptional reactivity with samples from various species and is optimized for use in applications such as Western blotting. By binding to the S protein, this antibody facilitates the detection and analysis of this critical molecule in a variety of cell types. Its versatility and reliability make it an essential tool for studies in virology, immunology, and vaccine development.
The S protein, also known as the spike protein, is a key player in the infectivity and pathogenesis of SARS-CoV-2, the virus responsible for COVID-19. Understanding the structure and function of this protein is vital for the development of effective diagnostic tools, therapeutics, and vaccines. The S antibody (PACO34410) provides researchers with a valuable resource for unraveling the mysteries surrounding this crucial viral component and advancing our knowledge in the fight against the ongoing pandemic.
Antibody Name:
S Antibody (PACO34410)
Antibody SKU:
PACO34410
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Bovine coronavirus
Immunogen:
Recombinant Bovine coronavirus Spike glycoprotein protein (326-540AA)
S1 attaches the virion to the cell membrane by binding to 9-O-acetylated sialic acid, containing proteins, initiating the infection.By similarity S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes (By similarity).
Synonyms:
Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1 (90B); Spike protein S2 (90A)], S
UniProt Protein Function:
S1 attaches the virion to the cell membrane by binding to 9-O-acetylated sialic acid containing proteins, initiating the infection.
