The RXRB Polyclonal Antibody (CAB18119) is a valuable tool for researchers studying RXRB, a key component of the retinoid X receptor (RXR) signaling pathway. This rabbit polyclonal antibody is highly specific to human RXRB and has been validated for use in Western blot applications. By binding to the RXRB protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and drug discovery.RXRB is a nuclear receptor that plays a crucial role in regulating gene expression in response to retinoic acid and other ligands.
Dysregulation of RXRB signaling has been linked to various diseases, including cancer and metabolic disorders. By studying RXRB activity, researchers can gain insight into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.In summary, the RXRB Polyclonal Antibody offers researchers a reliable tool for investigating the function of RXRB in various biological processes. Its high specificity and sensitivity make it a valuable asset for studies aiming to unravel the complex roles of RXRB in health and disease.
Product Name:
RXRB Rabbit Polyclonal Antibody
SKU:
CAB18119
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human RXRB (NP_001257330.1).
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
6257
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RXRB Rabbit pAb antibody (CAB18119) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
