The RXRA Polyclonal Antibody (CAB15242) is a valuable tool for researchers studying the retinoid X receptor alpha (RXRA), a nuclear receptor involved in gene regulation and various cellular processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the RXRA protein, this antibody allows for the detection and analysis of RXRA in different cell types, making it ideal for studies in molecular biology, pharmacology, and cancer research.RXRA plays a crucial role in mediating the effects of retinoids, which are essential for cell growth, differentiation, and development.
Dysregulation of RXRA has been implicated in various diseases, including cancer, metabolic disorders, and neurodegenerative diseases. Therefore, understanding the function and activity of RXRA is important for developing targeted therapies that modulate its signaling pathways in disease contexts.Overall, the RXRA Polyclonal Antibody (CAB15242) is a valuable tool for researchers investigating the role of RXRA in cellular processes and disease development. Its specificity and reliability make it a trusted reagent for Western blot analysis, enabling precise and accurate detection of RXRA in experimental settings.
Product Name:
RXRα Rabbit Polyclonal Antibody
SKU:
CAB15242
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RXRα (NP_002948.1).
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6256
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RXRα antibody (CAB15242) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
