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RUVBL1 Monoclonal Antibody [PAT1D6AT] (CPAB0655)

SKU:
CPAB0655
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1D6AT
Applications:
WB
ELISA
FC
€149

Description

system_update_alt Datasheet

RUVBL1 Monoclonal Antibody [PAT1D6AT] (CPAB0655)

The RUVBL1 Polyclonal Antibody (CPAB0655) is a valuable tool for research involving the RuvB-like protein 1 (RUVBL1), a key player in various cellular processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the RUVBL1 protein, this antibody allows for the detection and analysis of RUVBL1 in different cell types, making it a versatile option for studies in molecular biology, cell biology, and cancer research.

RUVBL1 is known for its involvement in chromatin remodeling, DNA repair, and transcriptional regulation, making it a crucial component in maintaining genomic stability and cellular function. Dysfunction of RUVBL1 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its significance as a potential therapeutic target. Research on RUVBL1 is essential for gaining insights into its molecular mechanisms and developing novel treatments for RUVBL1-associated diseases.

Product Name:RUVBL1 Antibody
Product Sku:CPAB0655
Size:5μg
Host Species:Mouse
Immunogen:Anti-human RUVBL1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human RUVBL1 amino acids 1-456 purified from Ecoli.
Clone:PAT1D6AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:RUVBL1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:RUVBL1 is part of NuA4 histone acetyltransferase complex which participates in transcriptional activation of specific genes mainly by acetylation of nucleosomal histone H4 and H2A. This complex is essential for the activation of transcriptional programs associated with oncogene and proto oncogene mediated growth induction, tumor suppressor mediated growth arrest.
Synonyms:ECP54, RUVBL1, INO80H, NMP238, PONTIN, Pontin52, RVB1, TIH1, TIP49, TIP49A, RuvB-Like 1, EC 3.6.4.12, TIP60-associated protein 54-alpha, TAP54-alpha.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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