The RUVBL1 Polyclonal Antibody (CAB5723) is a valuable tool for researchers studying the RUVBL1 protein, a key component of several protein complexes involved in various cellular processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the RUVBL1 protein, this antibody allows for the detection and analysis of RUVBL1 in a variety of cell types, making it an excellent choice for studies in molecular biology and cancer research.
RUVBL1, also known as pontin, is a conserved AAA+ ATPase that plays a crucial role in chromatin remodeling, DNA repair, and transcriptional regulation. Its involvement in these essential cellular processes makes it a promising target for research into diseases such as cancer and genetic disorders. By delving into the functions of RUVBL1, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify novel therapeutic approaches.
Product Name:
RUVBL1/TIP49A/PONTIN Rabbit Polyclonal Antibody
SKU:
CAB5723
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human RUVBL1/TIP49A/PONTIN (NP_003698.1).
This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8607
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RUVBL1/TIP49A/PONTIN Rabbit pAb (CAB5723) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 15s.
