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RUNX3 Rabbit Polyclonal Antibody (CAB7303)

SKU:
CAB7303
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-RUNX3 Antibody CAB7303
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-RUNX3 Antibody CAB7303
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RUNX3 Rabbit Polyclonal Antibody
SKU:CAB7303
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 286-415 of human RUNX3 (NP_004341.1).
Sequence:GTSI SSLS VAGM PATS RFHH TYLP PPYP GAPQ NQSG PFQA NPSP YHLY YGTS SGSY QFSM VAGS SSGG DRSP TRML ASCT SSAA SVAA GNLM NPSL GGQS DGVE ADGS HSNS PTAL STPG RMDE AVWR PY
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:100
Synonyms:AML2; CBFA3; PEBP2aC; RUNX3
Positive Sample:Mouse stomach
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:44kDa
Observed MW:49kDa

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:864
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of Mouse stomach, using RUNX3 antibody (CAB7303) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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