RUNX1/2/3 Rabbit Polyclonal Antibody (CAB2055)
- SKU:
- CAB2055
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RUNX1/2/3 Rabbit Polyclonal Antibody |
SKU: | CAB2055 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 171-260 of human RUNX1 (NP_001001890.1). |
Sequence: | DGPR EPRR HRQK LDDQ TKPG SLSF SERL SELE QLRR TAMR VSPH HPAP TPNP RASL NHST AFNP QPQS QMQD TRQI QPSP PWSY DQSY QY |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:700 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; CBF2alpha; AML1-EVI-1; PEBP2alpha; RUNX1 |
Positive Sample: | Molt-4 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 49kDa |
Observed MW: | 55kDa |
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 861 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |