RUNX1/2/3 Rabbit Monoclonal Antibody (CAB5115)
- SKU:
- CAB5115
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RUNX1/2/3 Rabbit Monoclonal Antibody |
SKU: | CAB5115 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 354-453 of human RUNX1/2/3 (NP_001001890.1). |
Sequence: | LPPP YPGS SQAQ GGPF QASS PSYH LYYG ASAG SYQF SMVG GERS PPRI LPPC TNAS TGSA LLNP SLPN QSDV VEAE GSHS NSPT NMAP SARL EEAV WRPY |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:10001:500-1:1000 |
Synonyms: | AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2aB; PEBP2alpha; RUNX1/2/3 |
Positive Sample: | HeLa,293T,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 51kDa |
Observed MW: | 45-55kDa |
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Purification Method: | Affinity purification |
Gene ID: | 861/864/860 |
Clone Number: | ARC1162 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |