RUFY3 Rabbit Polyclonal Antibody (CAB12896)
- SKU:
- CAB12896
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | RUFY3 Rabbit Polyclonal Antibody |
SKU: | CAB12896 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-65 of human RUFY3 (NP_055776.1). |
Sequence: | MSAL TPPT DMPT PTTD KITQ AAME TIYL CKFR VSMD GEWL CLRE LDDI SLTP DPEP THED PNYL M |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RIPX; SINGAR1; ZFYVE30; RUFY3 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Endomembrane system, Perikaryon, filopodium, growth cone, invadopodium, lamellipodium. |
Calculated MW: | 53kDa |
Observed MW: | 56kDa |
This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 22902 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |