The RTP4 Polyclonal Antibody (PAC038958) is a crucial tool for researchers studying RTP4, a protein involved in neurotransmitter release and synaptic transmission. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for various research applications such as Western blotting.RTP4, also known as receptor expression enhancing protein 4, plays a key role in promoting the cell surface expression of certain receptors involved in neurotransmission. Its function in regulating synaptic activity makes it a valuable target for studies focusing on neurological disorders, such as Alzheimer's disease and schizophrenia.
By investigating the mechanisms of RTP4, researchers can gain valuable insights into the underlying pathophysiology of these conditions and develop potential therapeutic interventions.Overall, the RTP4 Polyclonal Antibody is a reliable tool for investigating the function and expression of RTP4 in neurological research, offering researchers the opportunity to deepen their understanding of synaptic transmission and develop novel treatment strategies for neurological disorders.
Western blot. All lanes: RTP4 antibody at 5µg/ml. Lane 1: K562 whole cell lysate. Lane 2: Mouse thymus tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 28 kDa. Observed band size: 28 kDa.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO38958 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO38958 at dilution of 1:100.
Background:
Probable chaperone protein which facilitates trafficking and functional cell surface expression of some G-protein coupled receptors (GPCRs). Promotes functional expression of the bitter taste receptor TAS2R16. Also promotes functional expression of the opioid receptor heterodimer OPRD1-OPRM1 (By similarity).
Synonyms:
Receptor-transporting protein 4 (28 kDa interferon-responsive protein) (3CxxC-type zinc finger protein 4), RTP4, IFRG28 Z3CXXC4
UniProt Protein Function:
RTP4: Belongs to the TMEM7 family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 3q27.3Cellular Component: cytoplasm; integral to membraneMolecular Function: olfactory receptor binding; protein bindingBiological Process: detection of chemical stimulus involved in sensory perception of bitter taste; protein insertion into membrane; protein targeting to membrane
