UniProt Protein Function: | RTN4IP1: Appears to be a potent inhibitor of regeneration following spinal cord injury. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: MitochondrialChromosomal Location of Human Ortholog: 6q21 |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, mental retardation, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
UniProt Code: | Q8WWV3 |
NCBI GenInfo Identifier: | 76789669 |
NCBI Gene ID: | 84816 |
NCBI Accession: | Q8WWV3.2 |
UniProt Secondary Accession: | Q8WWV3,Q8N9B3, Q8WZ66, Q9BRA4 |
UniProt Related Accession: | Q8WWV3 |
Molecular Weight: | 24,936 Da |
NCBI Full Name: | Reticulon-4-interacting protein 1, mitochondrial |
NCBI Synonym Full Names: | reticulon 4 interacting protein 1 |
NCBI Official Symbol: | RTN4IP1Â Â |
NCBI Official Synonym Symbols: | NIMP; OPA10Â Â |
NCBI Protein Information: | reticulon-4-interacting protein 1, mitochondrial |
UniProt Protein Name: | Reticulon-4-interacting protein 1, mitochondrial |
UniProt Synonym Protein Names: | NOGO-interacting mitochondrial protein |
Protein Family: | Reticulon-4-interacting protein |
UniProt Gene Name: | RTN4IP1Â Â |
UniProt Entry Name: | RT4I1_HUMAN |