The RTN1 Polyclonal Antibody (CAB16427) from AssayGenie is a valuable tool for researchers studying the reticulon 1 protein, which is involved in various cellular processes including membrane trafficking and neurodegenerative diseases. This polyclonal antibody is produced in rabbits and has been validated for use in Western blot applications, providing reliable detection of RTN1 in human samples.RTN1, a member of the reticulon family of proteins, is known to play a role in shaping the endoplasmic reticulum membrane and regulating intracellular transport pathways.
Dysregulation of RTN1 has been linked to neurodegenerative diseases such as Alzheimer's and Parkinson's disease, making it a promising target for therapeutic interventions.With its high reactivity and specificity for RTN1, the CAB16427 antibody is an excellent tool for investigating the function and regulation of this important protein in both normal and disease states. Researchers in the fields of neuroscience, cell biology, and drug discovery will find this antibody invaluable for their studies.
Product Name:
RTN1 Rabbit Polyclonal Antibody
SKU:
CAB16427
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human RTN1 (NP_066959.1).
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6252
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse lung, using RTN1 Rabbit pAb (CAB16427) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5 min.
