RSPO3 Rabbit Polyclonal Antibody (CAB8389)
- SKU:
- CAB8389
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | RSPO3 Rabbit Polyclonal Antibody |
SKU: | CAB8389 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RSPO3 (NP_116173.2). |
Sequence: | MHLR LISW LFII LNFM EYIG SQNA SRGR RQRR MHPN VSQG CQGG CATC SDYN GCLS CKPR LFFA LERI GMKQ IGVC LSSC PSGY YGTR YPDI NKCT KCKA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PWTSR; THSD2; CRISTIN1; RSPO3 |
Positive Sample: | A-549,NCI-H460,HeLa,Mouse liver,Mouse skin,Mouse brain,Mouse spinal cord,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 31kDa |
Observed MW: | 39kDa |
This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development.
Purification Method: | Affinity purification |
Gene ID: | 84870 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |