The RSPH3 Antibody (PAC037294) is a polyclonal antibody designed for research involving RSPH3, a protein involved in ciliary function and motility. The antibody, raised in rabbits, demonstrates high reactivity with human samples and is validated for use in various applications, including Western blot and immunofluorescence assays. It specifically binds to the RSPH3 protein, allowing for accurate detection and analysis in a variety of cell types.RSPH3 is a key player in the maintenance of ciliary structure and function, which is critical for cellular movement and development.
Dysregulation of RSPH3 has been associated with ciliary dysfunction disorders, such as primary ciliary dyskinesia, highlighting its importance in respiratory and reproductive health. Further research on RSPH3 can provide insight into the mechanisms underlying these conditions and aid in the development of targeted therapies.
Antibody Name:
RSPH3 Antibody (PACO37294)
Antibody SKU:
PACO37294
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Radial spoke head protein 3 homolog protein (1-275AA)
Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia.
Synonyms:
Radial spoke head protein 3 homolog (A-kinase anchor protein RSPH3) (Radial spoke head-like protein 2), RSPH3, RSHL2 RSP3
UniProt Protein Function:
RSHL2: Belongs to the flagellar radial spoke RSP3 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 6q25.3Molecular Function: protein bindingDisease: Ciliary Dyskinesia, Primary, 32
