The RSK1 (p90) Rabbit Monoclonal Antibody (CAB4695) is a vital tool for researchers studying the RSK1 protein, a key player in cell signaling pathways that regulate cell growth, division, and survival. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot experiments.RSK1, a member of the ribosomal S6 kinase (RSK) family, is involved in various cellular processes, including gene expression and cell proliferation. Its dysregulation has been linked to cancer development and progression, making it a potential target for cancer therapies.
By targeting the RSK1 protein, researchers can gain insights into its function and pave the way for innovative treatments for cancer and other related diseases.The RSK1 (p90) Rabbit Monoclonal Antibody (CAB4695) offers reliable detection and analysis of RSK1 protein levels in different cell types, making it an invaluable tool for studies in oncology and cell biology. By understanding the role of RSK1 in cellular signaling pathways, researchers can uncover new therapeutic strategies and potentially improve patient outcomes in the future.
Product Name:
p90Rsk/RSK1/RPS6KA1 Rabbit Monoclonal Antibody
SKU:
CAB4695
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p90Rsk/RSK1/RPS6KA1 (Q15418).
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
6195
Clone Number:
ARC1096
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using p90Rsk/RSK1/RPS6KA1 Rabbit mAb (CAB4695) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.