The RSAD2 Polyclonal Antibody (CAB8271) is a valuable tool for research involving RSAD2, a protein known for its antiviral activity in the immune response. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding to the RSAD2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in virology and immunology.RSAD2, also known as viperin, plays a crucial role in the innate immune response to viral infections by inhibiting virus replication within infected cells.
Its importance in antiviral defense makes RSAD2 a key target for research into infectious diseases and immune responses against pathogens. Understanding the function of RSAD2 can provide insights for developing novel antiviral therapies and vaccines that target this pathway for enhanced protection against viral infections.
Product Name:
RSAD2 Rabbit Polyclonal Antibody
SKU:
CAB8271
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 118-361 of human RSAD2 (NP_542388.2).
The protein encoded by this gene is an interferon-inducible antiviral protein that belongs to the S-adenosyl-L-methionine (SAM) superfamily of enzymes. The protein plays a role in cellular antiviral response and innate immune signaling. Antiviral effects result from inhibition of viral RNA replication, interference in the secretory pathway, binding to viral proteins and dysregulation of cellular lipid metabolism. The protein has been found to inhibit both DNA and RNA viruses, including influenza virus, human immunodeficiency virus (HIV-1) and Zika virus.
Purification Method:
Affinity purification
Gene ID:
91543
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RSAD2 Rabbit pAb (CAB8271) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
