The RSAD1 Antibody (PAC023472) is a polyclonal antibody developed for research involving RSAD1, a protein involved in the innate immune response to viral infections. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It targets the RSAD1 protein, allowing for precise detection and analysis in various cell types, making it an excellent tool for studies in virology and immunology.
RSAD1, also known as viperin, plays a critical role in the host defense against viruses by inhibiting viral replication and promoting antiviral immune responses. Its role in the innate immune system makes it a promising target for research into antiviral therapies and viral pathogenesis. Understanding the function of RSAD1 is essential for the development of novel strategies to combat viral infections and improve antiviral immunity.
Synthesized peptide derived from internal of human RSAD1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HeLa cells, using RSAD1 antibody.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using RSAD1 antibody.
Background:
May be involved in porphyrin cofactor biosynthesis By similarity.
Synonyms:
EC 1.3.99.-; Oxygen-independent coproporphyrinogen III oxidase-like protein RSAD1;
UniProt Protein Function:
RSAD1: May be involved in porphyrin cofactor biosynthesis. Belongs to the anaerobic coproporphyrinogen-III oxidase family.Protein type: EC 1.3.99.-; OxidoreductaseChromosomal Location of Human Ortholog: 17q21.33Cellular Component: mitochondrionMolecular Function: 4 iron, 4 sulfur cluster binding; coproporphyrinogen oxidase activity; metal ion bindingBiological Process: porphyrin biosynthetic process