The RRP1 Polyclonal Antibody (CAB17569) is a valuable tool for researchers studying RRP1, a protein involved in ribosomal RNA processing. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the RRP1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for investigations in molecular biology and cellular research.RRP1 is a crucial player in the intricate process of ribosomal RNA maturation, essential for the production of functional ribosomes. Dysregulation of RRP1 has been linked to abnormalities in ribosomal RNA processing, leading to disruptions in protein synthesis and cellular function.
Understanding the role of RRP1 is vital for deciphering the mechanisms underlying diseases such as cancer and genetic disorders, where disruptions in ribosomal RNA processing can have profound consequences on cell growth and survival.The RRP1 Polyclonal Antibody provides researchers with a powerful tool to study the function and regulation of RRP1, facilitating investigations into the molecular mechanisms underlying ribosomal RNA processing and its impact on cellular physiology. This antibody is an invaluable resource for advancing our understanding of fundamental biological processes and identifying potential therapeutic targets for diseases associated with defects in ribosomal RNA metabolism.
Product Name:
RRP1 Rabbit Polyclonal Antibody
SKU:
CAB17569
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-253 of human RRP1 (NP_003674.1).
The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA.
Purification Method:
Affinity purification
Gene ID:
8568
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RRP1 Rabbit pAb (CAB17569) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
