The RRM2 Rabbit Monoclonal Antibody (CAB3424) is a valuable tool for researchers studying RRM2, a key enzyme involved in DNA replication and repair processes. This antibody, developed in rabbits, shows high specificity and sensitivity for human samples, making it ideal for use in various research applications such as Western blotting.RRM2 is essential for maintaining genomic stability and is often dysregulated in cancer, making it a promising target for novel cancer therapies. By targeting RRM2, researchers can gain valuable insights into the mechanisms underlying cancer development and progression.
With its high reactivity and reliability, the RRM2 Rabbit Monoclonal Antibody is a valuable asset for researchers in the fields of oncology, molecular biology, and genetics. Its ability to detect and analyze RRM2 protein expression in different cell types makes it a versatile tool for advancing our understanding of DNA replication and repair pathways in health and disease.
Product Name:
RRM2 Rabbit Monoclonal Antibody
SKU:
CAB3424
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 10-117 of human RRM2 (P31350).
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.
Purification Method:
Affinity purification
Gene ID:
6241
Clone Number:
ARC0775
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RRM2 Rabbit mAb (CAB3424) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
