RRM1 Rabbit Polyclonal Antibody (CAB1152)
- SKU:
- CAB1152
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RRM1 Rabbit Polyclonal Antibody |
SKU: | CAB1152 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 593-792 of human RRM1 (NP_001024.1). |
Sequence: | IRNS LLIA PMPT ASTA QILG NNES IEPY TSNI YTRR VLSG EFQI VNPH LLKD LTER GLWH EEMK NQII ACNG SIQS IPEI PDDL KQLY KTVW EISQ KTVL KMAA ERGA FIDQ SQSL NIHI AEPN YGKL TSMH FYGW KQGL KTGM YYLR TRPA ANPI QFTL NKEK LKDK EKVS KEEE EKER NTAA MVCS LENR DECL MCGS |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | R1; RR1; RIR1; RRM1 |
Positive Sample: | HeLa,A-549,Raji,Mouse testis,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 90kDa |
Observed MW: | 90kDa |
This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 6240 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |