The RRM1 Polyclonal Antibody (CAB13348) is a valuable tool for researchers studying RRM1, a key enzyme involved in DNA synthesis and repair. This antibody, produced in rabbits, is highly specific for human samples and has been validated for Western blot applications. It binds to the RRM1 protein, allowing for precise detection and analysis in a variety of cell types.RRM1 is essential for maintaining genomic integrity and is often dysregulated in cancer cells, making it a promising target for cancer research. By targeting RRM1, researchers can gain insights into the mechanisms of tumorigenesis and potentially develop new therapeutic strategies.
Furthermore, understanding the role of RRM1 in DNA replication and repair can provide valuable information for the development of personalized cancer treatments.In conclusion, the RRM1 Polyclonal Antibody is a powerful tool for research in oncology and molecular biology, offering high specificity and sensitivity for the detection of RRM1 protein in various experimental settings. Its use can contribute to advancing our knowledge of cancer biology and potentially lead to the development of novel anti-cancer therapies.
Product Name:
RRM1 Rabbit Polyclonal Antibody
SKU:
CAB13348
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 593-792 of human RRM1 (NP_001024.1).
This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6240
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RRM1 Rabbit pAb (CAB13348) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
