RRBP1 Rabbit Polyclonal Antibody (CAB12239)
- SKU:
- CAB12239
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | RRBP1 Rabbit Polyclonal Antibody |
SKU: | CAB12239 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human RRBP1 (NP_004578.2). |
Sequence: | MDIY DTQT LGVV VFGG FMVV SAIG IFLV STFS MKET SYEE ALAN QRKE MAKT HHQK VEKK KKEK TVEK KGKT KKKE EKPN GKIP DHDP APNV TVLL REPV RAPA VAVA PTPV QPPI IVAP VATV PAMP QEKL ASSP KDKK |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | RRp; hES; p180; ES130; ES/130; RRBP1 |
Positive Sample: | U-87MG,HeLa,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Single-pass type III membrane protein. |
Calculated MW: | 152kDa |
Observed MW: | 120kDa |
This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.
Purification Method: | Affinity purification |
Gene ID: | 6238 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |