The RragA Polyclonal Antibody (CAB7771) is a valuable tool for researchers studying RragA, a protein involved in regulating cell growth and metabolism. This antibody, produced in rabbits, is highly specific for RragA in human samples and is validated for use in Western blotting applications. By binding to RragA, this antibody enables accurate detection and analysis of the protein in various cell types, making it an essential component for studies in cell biology and metabolic regulation.RragA is a key player in the mTORC1 signaling pathway, a critical regulator of cell growth and proliferation.
Dysregulation of this pathway has been implicated in various diseases, including cancer and metabolic disorders. Research on RragA is instrumental in understanding the mechanisms underlying these conditions and may lead to the development of targeted therapies to treat them. The RragA Polyclonal Antibody provides researchers with a reliable tool to explore the functions of RragA and its potential as a therapeutic target.
Product Name:
RRAGA Rabbit Polyclonal Antibody
SKU:
CAB7771
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 213-313 of human RRAGA (NP_006561.1).
Enables several functions, including GTP binding activity; protein dimerization activity; and ubiquitin protein ligase binding activity. Involved in several processes, including cellular response to amino acid starvation; negative regulation of autophagy; and positive regulation of TORC1 signaling. Located in lysosome and nucleus. Colocalizes with GATOR1 complex.
Purification Method:
Affinity purification
Gene ID:
10670
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RRAGA antibody (CAB7771) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
