The RRAGA Polyclonal Antibody (CAB15134) is a valuable tool for researchers studying RRAGA, a key regulator of the mTOR pathway involved in cell growth and metabolism. This antibody is produced in rabbits and demonstrates high reactivity with human samples, making it ideal for Western blot applications. By targeting the RRAGA protein, this antibody enables precise detection and analysis in various cell types, offering insights into the role of RRAGA in cellular processes.RRAGA is known for its significance in the mTOR signaling pathway, which plays a critical role in regulating cell growth, proliferation, and survival. Dysregulation of this pathway has been implicated in various diseases, including cancer and metabolic disorders.
Therefore, understanding the function of RRAGA is essential for unraveling the molecular mechanisms underlying these conditions and potentially identifying therapeutic targets.By utilizing the RRAGA Polyclonal Antibody (CAB15134) in research, scientists can gain valuable insights into the role of RRAGA in cellular signaling pathways and its potential implications for disease pathology. This antibody provides a reliable tool for investigating the intricate mechanisms of the mTOR pathway and its involvement in various physiological and pathological processes.
Product Name:
RRAGA Rabbit Polyclonal Antibody
SKU:
CAB15134
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 213-313 of human RRAGA (NP_006561.1).
Enables several functions, including GTP binding activity; protein dimerization activity; and ubiquitin protein ligase binding activity. Involved in several processes, including cellular response to amino acid starvation; negative regulation of autophagy; and positive regulation of TORC1 signaling. Located in lysosome and nucleus. Colocalizes with GATOR1 complex.
Purification Method:
Affinity purification
Gene ID:
10670
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RRAGA Rabbit pAb (CAB15134) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.